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Social and behavioral prevention and treatment

Advance innovative research and collaborations that prevent or reduce tobacco use and the impact of tobacco-related diseases among California’s priority groups (see a list of priority groups under Research Award).

Tobacco use continues to cause disproportionately high rates of morbidity and mortality from cancers, cardiovascular and lung diseases, oral diseases, and reduced quality of life among California priority groups. Tobacco-related health disparities (TRHDs) devastate individuals, families, communities and the economy.

Social Determinants of Health

Multiple complex factors contribute to TRHDs. Research focused on reducing TRHDs should include innovative and creative approaches to measure and mitigate at least one social determinant of health that is associated with tobacco product use, tobacco control policy, or tobacco-related diseases. Understanding and reducing TRHDs requires consideration of intersectional groups and the interaction of individual, interpersonal/social, community/school, institutional, and policy factors across the tobacco use continuum and over the life span. Cultural factors and experiences with discrimination are important to consider when addressing the impact of environment, structural factors, and institutional/government policy on health.

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Collaborations and Community Engagement

TRDRP encourages researchers, educators, and academic institutions to collaborate closely with and seek input from nonprofit, community-based organizations, health centers and clinics, schools and other educational settings, tobacco control advocates and programs, American Indian tribal organizations, immigrant service organizations, employment development agencies, post-incarceration service agencies, migrant farmworker support agencies, and policymakers.

Community-based organizations with available infrastructure to manage grant funding are encouraged to apply for TRDRP funding and may play a lead role on a community-academic partnered participatory research project; however, community organizations and their affiliates should participate on a research project to the extent that their capacity and available resources allow. Collaborative research partnerships are needed:

  • To address a tobacco-related research question(s) that community members have identified as critically important and that has a negative impact on a priority group in their community
  • Between health care practitioners and academic researchers to develop a standard process for addressing tobacco product use that can be employed in clinical settings, and to promote systems level change in cessation-related clinical activities and healthcare policy
  • To collect research findings that clarify the extent TRHDs affect a community and inform health protective public policy and tobacco control programming
  • To build capacity and leadership among community-based organizations and other nonprofits for scientific research
  • To train and prepare the next generation of leaders and advocates in tobacco control research

TRDRP particularly encourages researchers to work with tribal leadership on commercial tobacco health and policy issues. In pursuing this line of research, investigators are expected to distinguish commercial from ceremonial tobacco use, respect the sovereignty of American Indian lands, and seek cooperation at all levels when working in these venues, including with tribal members and tribal leaders.

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Optimizing tobacco-related prevention and treatment interventions

  • Impactful health service research that contributes to sustainable systems change in the clinical management of nicotine dependence and sustained coverage of tobacco treatments by health plans
  • Examining the benefits and consequences of culturally-tailored tobacco treatments in clinical, school, or other community settings. Pilot tests and validation studies of promising interventions that help e-cigarette users with vaping cessation
  • Mechanistic studies that highlight intervention components that contribute to quitting e-cigarettes regardless of product type used
  • Health behavior change interventions that promote cessation of multiple tobacco product use, flavored tobacco product use, and tobacco-cannabis co-use
  • Development and testing of new theories that support culturally sensitive health communications that consider intersectional identity and cultural factors in tobacco prevention and treatment
  • Innovative health messaging strategies and communication toolkits for multiple tobacco product use, flavored tobacco product use, and tobacco-cannabis co-use
  • Development and testing the efficacy and effectiveness of social media and mobile technologies in treatments to reduce or eliminate multiple tobacco product use, flavored tobacco use, and tobacco-cannabis co-use
  • Scientific evaluations of tobacco prevention and treatment interventions informed by practice-based or community-based knowledge
  • Testing evidence-based interventions efficacious for other health issues for similar efficacy or effectiveness in tobacco prevention and treatment interventions and community/school programs

Harm reduction interventions

  • Testing the extent to which electronic smoking devices result in long-term elimination of combustible tobacco use or substitution
  • Tracking health effects among long-term users of electronic smoking devices
  • Developing intervention and mechanistic studies focused on sustained nicotine abstinence among successful cigarette quitters
  • Examining the benefits and consequences of sustained use of multiple tobacco products
  • Characterizing health effects and changes in dependence after long-term nicotine use, or the co-use of cannabis and tobacco products

Prevent and reduce child, adolescent and young adult tobacco product use and secondhand smoke exposure

  • Development of psychometrically rigorous measures that assess utility of youth tobacco prevention activities in and outside of classroom settings
  • Scientific evaluations of practice-informed tobacco prevention efforts in diverse school, after school, and non-traditional education settings
  • Development of youth-focused health communication strategies that address menthol and flavored tobacco, heated tobacco, pod mod tobacco, or cannabis use
  • Community-based studies focused on reducing youth exposure to secondhand tobacco products and cannabis smoke and vapor

Surveillance of health effects and contextual factors of new and emerging tobacco product use and cannabis use

  • Examination of the prevalence and initiation of multiple tobacco product use and tobacco-cannabis co-use among priority groups
  • Identifying short- and long-term health effects of tobacco-cannabis co-use
  • Development of psychometrically rigorous measures that accurately capture use patterns and dependence from use of electronic smoking devices, heated tobacco, flavored combustible tobacco, and tobacco-cannabis co-use
  • Elucidation of social determinants associated with multiple tobacco product use and tobacco-cannabis co-use

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